Esterified estrogens are blends of various estrogens, a kind of female hormone. Estrogens instigate enlargement and improvement of the female sex organs and the preservation of sex features like development of underarm and pubic hair and determining body curves and skeleton. It can also enhance emissions from the cervix and development of the exterior coating of the uterus. Do these medications affect libido?
Uses of esterified estrogens
This medication is recommended for the remedy of the usual symptoms connected to menopause. It is also important for extreme and distressing uterine blood loss, prostate cancer, and for the avoidance of bone breakage connected to osteoporosis, heart attacks and strokes. Its usual recommended dosage is once a day.
Contraindications of esterified estrogens
The following results are seen when esterified estrogens are used in combination with other drugs:
- Cyclosporine levels. Estrogens have the ability to prevent destruction of cyclosporine. When cyclosporine levels are improved in the blood, kidney or liver injury is the end result.
- Liver disease. Estrogens seem to enhance the danger of liver problem in individuals getting dantrolene from an unidentified organism. It is considered that females more than 35 years old and with an existing liver problem are in high risk for this problem.
- Decreased efficiency of anticoagulants. Estrogens enhance your liver’s capability to produce substances that are needed for blood clotting. The anticoagulant warfarin results to this situation. It is important that blood clotting is closely observed if estrogen will be given. If your blood clots quickly, the dosage of warfarin must be enhanced.
- Decreased effectiveness. Just like in vaginal creams, the use of esterified estrogens must be given with caution to individuals using other kinds of drugs like rifampin, barbiturates, tegretol, griseofulvin, dilantin and primidone. These drugs can enhance the removal of estrogen by improving the liver’s capacity to destroy it. These can also affect the advantageous function of estrogens.
Side Effects of esterified estrogens
The most common side effects associated with the use of esterified estrogens include the following:
- Blood clots. These are considered infrequent but are severe side effects of estrogen treatment due to excessive use with elevated amounts. Individuals who smoke a lot are in great danger than those who are not smoking. It is advised that you should stop smoking if you want to receive estrogen therapy.
- Uterine cancer. Estrogens can support an increase of the coating of the uterus and enhance the danger of endometrial cancer. It is important that you should incorporate progestin to estrogen treatment to avoid the development of endometrial cancer.
- Breast cancer. There are some existing disagreement on the data in connection with estrogen treatment and breast cancer. It is not yet clearly established if an addition of progestin to an estrogen treatment can decrease the danger of breast cancer.
Since there are medical conditions that may result with the improper administration of esterified estrogens, there are great tendencies that libido levels will get affected as well. Proper monitoring of the patient should be done to get rid of these problems. Patients are advised to work closely with their physicians.
